实验室简介
Our research consists of both mechanistic and synthetic studies in organic chemistry with an emphasis on in-depth mechanistic understanding. In particular, we focus on the key reactive intermediates in important reactions, wherein the elucidation of their structure, formation mechanism, and reaction pattern are the core content of our research. Since 2014, we have been working on several representative reaction systems, and our studies have provided useful mechanistic insights that changed the established cognition of related fields and inspired the design of new reactions and catalysts.
Chemistry
Background: Diboron(4) compounds were prevalently employed in the borylation reactions. We have discovered that pyridine derivatives could catalyze the transition-metal-free borylation reaction of aryl halides with diboron(4) compounds. Detailed mechanistic study revealed an unprecedented reaction mode of pyridine and diboron(4) in the presence of an alcoholate to generate a novel N-boryl pyridyl anion key intermediate, which was found to enable a series of new reactions that constitute...