18 of the amino acids were each encoded by more than one codon, but the synonymous codons were not used with equal frequency, a phenomenone known as the "codon usage bias". It is commonly accepted that the evolution of codon usage bias was underlied by mutation, drift and selection. We explored the relative contribution of chance (mutation and drift) and necessity (selection) in determining the codon usage bias of cells and genes.
The role of mutation, drift and selection in evolution of codon usage bias
创建: Dec 31, 2020 | 10:39